Ross Arena PT, Ph.D., F.A.H.A., F.A.C.S.M., F.A.A.C.V.P.R.
Associate professor
E-mail: raarena@vcu.edu
Professional interests
Ross Arena teaches courses in cardiopulmonary physical therapy, exercise physiology and pharmacology in the Doctor of Physical Therapy program. Arena is a fellow and active member of the American Heart Association, American College of Sports Medicine and American Association of Cardiovascular and Pulmonary Rehabilitation. Arena’s primary research interest is investigating the clinical value of cardiopulmonary exercise testing and training in the heart failure population.
Education
- Ph.D. Physiology/Physical Therapy (2001), Virginia Commonwealth University, School of Medicine, Richmond, Va.
- M.S. Physical Therapy (1997), Virginia Commonwealth University, Richmond, Va.
- B.S. Human Performance (1993), Southern Connecticut State University, New Haven, Conn.
Selected publications
Arena R, Myers J, Peberdy MA, Bensimhon D, Chase P, Guazzi M. The ventilatory classification system effectively predicts hospitalization in patients with heart failure. Journal of Cardiopulmonary Rehabilitation and Prevention. 2008;28:195-198.
Arena R, Myers J, Guazzi M. The clinical importance of cardiopulmonary exercise testing and aerobic training in patients with heart failure. Brazilian Journal of Physical Therapy. 2008;12:75-87.
Arena R, Owens D, Arevalo J, Smith K, Mohiddon S, McAreavey D, Ulisney K. Tripodi D, Fananapazir L, Plehn J. Ventilatory efficiency and resting hemodynamics in hypertrophic cardiomyopathy. Medicine and Science in Sports and Exercise. 2008;40:799-805.
Arena R, Myers J, Guazzi G. The Clinical and Research Applications of Aerobic Capacity and Ventilatory Efficiency in Heart Failure: An Evidence-Based Review. Heart Failure Reviews. 2008;13:245-269.
Arena R, Myers J, Abella J, Peberdy M, Bensimhon D, Chase P, Guazzi M. The influence of body mass index on the oxygen uptake efficiency slope in patients with heart failure. International Journal of Cardiology. 2008;125:270-272.
Arena R, Myers J, Abella J, Peberdy M, Pinkstaff S, Bensimhon D, Chase P, Guazzi M. The Prognostic Value of Timing and Duration Characteristics of Exercise Oscillatory Ventilation in Patients with Heart Failure. Journal of Heart and Lung Transplantation. 2008;27:341-347.
Guazzi M, Arena R, Casali M, Guazzi MD. Evolving changes in lung interstial fluid content after acute myocardial infarction: pathophysiologic correlates. American Journal of Physiology; Heart and Circulatory Physiology. 2008;294:H1357-H1364.
Chase P, Arena R, Myers J, Abella J, Peberdy MA, Guazzi M, Bensimhon D. Relation of the prognostic value of ventilatory efficiency to body mass index in patients with heart failure. American Journal of Cardiology. 2008;101:348-352.
Arena R, Arrowood J, Fei D, Helm S, Kraft K. A diastolic blood pressure response during exercise is associated with dyslipidemia in apparently healthy subjects. Journal of Cardiopulmonary Rehabilitation and Prevention. 2008;28:38-42.
Guazzi M, Samaja M, Arena R, Vicenzi M, Guazzi MD. Long-term use of Sildenafil in the therapeutic management of heart failure. Journal of the American College of Cardiology. 2007;27:2136-2144.
Pagel-Langenickel I, Schwartz D, Arena R, Minerbi D, Johnson D, Waclawiw M, Cannon R, Tripodi D, Balaban R, Sack M. A discordance in rosiglitazone mediated insulin sensitization and skeletal muscle mitochondrial content/activity in type 2 diabetes mellitus. American Journal of Physiology; Heart and Circulatory Physiology. 2007;293:2659-2666.
Gambetta M, Dunn P, Nelson D, Herron B, Arena R. Impact of the implementation of telemanagement on a disease management
program in an elderly heart failure cohort. Progress in Cardiovascular Nursing. 2007;22:196-200.
Kraft K, Arena R, Arrowood J, Fei D. High aerobic capacity does not attenuate aortic stiffness in hypertensive subjects. American Heart Journal. 2007;154:976-982.
Arena R, Fei D, Arrowood J, Kraft K. Influence on aerobic fitness on aortic stiffness in apparently healthy Caucasian and African-American subjects. International Journal of Cardiology. 2007; 122:202-206.
Arena R, Myers J, Hsu L, Peberdy M, Pinkstaff S, Bensimhon D, Chase P, Vicenzi M, Guazzi M. The minute ventilation/carbon dioxide production slope is prognostically superior to the oxygen uptake efficiency slope. Journal of Cardiac Failure. 2007;13:462-469.
Arena R, Guazzi M, Myers J. Ventilatory abnormalities during exercise in heart failure: A mini review. Current Respiratory Medicine Reviews. 2007;3:179-187.
Arena R, Myers J, Williams M, Gulati M, Kligfield P, Balady G, Collins, E, Fletcher G. Assessment of functional capacity in clinical and research settings: An advisory from the Committee on Exercise, Rehabilitation, and Prevention, Council on Clinical Cardiology, American Heart Association. Circulation. 2007;116:329-343.
Guazzi M, Raimondo R, Arena R, Proserpio C, Braga S, Pedretti R. Exercise oscillatory ventilation predicts sudden cardiac death in heart failure patients. Journal of the American College of Cardiology. 2007;50:299-308.
Arena R, Shizukuda Y, Bolan C, Tripodi D, Yau Y, Smith K, Waclawiw MA, Leitman S, Rosing D. Heart rate recovery is lower following supine exercise in asymptomatic hereditary hemochromatosis subjects compared to healthy controls. Journal of Cardiopulmonary Rehabilitation and Prevention. 2007:27; 157-160.
Arena R, Myers J, Abella J, Peberdy M, Bensimhon D, Chase P, Guazzi M. Development of a ventilatory classification system in patients with heart failure. Circulation. 2007:115;2410-2417.
Guazzi M, Arena R, Reina G, Ascione N, Guazzi MD. Exercise oscillatory breathing and increased ventilation to CO2 production slope in heart failure: an unfavorable combination with high prognostic value. American Heart Journal. 2007:153; 859-867.
Arena R, Guazzi M, Myers J, Abella J. The prognostic value of ventilatory efficiency with beta-blocker therapy in heart failure. Medicine and Science in Sports and Exercise. 2007:39; 213-219.
Shizukuda Y, Bolan C, Tripodi D, Yau Y, Smith K, Arena R, Waclawiw M, Leitman S, Rosing D. Exercise capacity of cardiac asymptomatic hereditary hemochromatosis subjects. Medicine and Science in Sports and Exercise. 2007:39; 3-7.
Shizukuda Y, Tripodi D, Smith K, Arena R, Waclawiw M, Rosing D. Can we use heart rate recovery information from supine ergometry exercise? American Journal of Cardiology. 2006; 98:1297-1298.
Arena R, Arrowood J, Fei D, Helm S, Kraft K. The relationship between c-reactive protein and other cardiovascular risk factors in men and women. Journal of Cardiopulmonary Rehabilitation. 2006; 26:323-329.
Arena R, Guazzi M, Myers J. Prognostic value of end-tidal carbon dioxide during exercise testing in heart failure. International Journal of Cardiology. 2007:117; 103-108.
Kraft K, Fei D, Shao X, Chang Y, Arena R. Improved aortic stiffness assessment in the elderly using a one-dimensional fluid displacement MR method. J Magn Reson Imaging. 2006; 24:603-610.
Arena R, Peberdy M. Short-term reliability of oxygen uptake on-kinetics in apparently healthy subjects. Journal of Cardiopulmonary Rehabilitation. Journal of Cardiopulmonary Rehabilitation. 2006; 26:219-223.
Guazzi M, Arena R, Myers J. Comparison of the prognostic value of cardiopulmonary exercise testing between male and female patients with heart failure. International Journal of Cardiology. 2006:113; 395-400.
Arena R, Peberdy M, Myers J, Guazzi M, Tevald M. Prognostic value of resting end-tidal carbon dioxide in patients with heart failure. International Journal of Cardiology. 2006;109:351-358.
Arena R, Guazzi M, Myers J. Peberdy M. Prognostic Value of Heart Rate Recovery in Patients with Heart Failure. American Heart Journal. 2006;151:851.e7-851.e13.
Arena R, Myers J, Aslam S, Varughese E, Peberdy M. Impact of time past exercise testing on prognostic variables in heart failure. International Journal of Cardiology. 2006;106:88-94.
Arena R, Guazzi M, Myers J. Peberdy M. Prognostic Characteristics of Cardiopulmonary Exercise Testing in Heart Failure: Comparing American and European Models. European Journal of Cardiovascular Prevention and Rehabilitation. 2005;12:562-567.
Arena R, Myers J, Abella J, Peberdy M. Influence of Heart Failure Etiology on the Prognostic Value of Peak VO2 and VE/VCO2 Slope. Chest. 2005;128:2812-2817.
Guazzi M, Myers J, Arena R. Cardiopulmonary exercise testing in the clinical practice and prognostic assessment of heart failure patients with preserved systolic function. Journal of the American College of Cardiology. 2005;46:1883-1890.
Arena R, Arrowood J, Fei D, Shao X, Kraft K. Effect of aerobic exercise training on aortic wave velocity in obese subjects: A report of five cases. Case Reports and Clinical Practice Review. 2005;6:211-215.
Arena R, Peberdy M. Reliability of resting end-tidal carbon dioxide in chronic heart failure.Journal of Cardiopulmonary Rehabilitation. 2005;25:177-180.
Arena R, Tevald M, Peberdy M. Influence of Etiology on Ventilatory Expired Gas and Prognosis in Heart Failure. International Journal of Cardiology. 2005;99:217-223.
Fei D, Arena R, Arrowood J, Kraft K. Relationship between Arterial Stiffness and Heart Rate Recovery in Apparently Healthy Adults. Vascular Health and Risk Management. 2005;1:85-89.
Arena R, Peberdy M, Tevald M, Turner T. Prognostic value of phase one of oxygen consumption on-kinetics in the heart failure population: a pilot report. Journal of Cardiopulmonary Rehabilitation. 2004;24:401-404.
Arena R, Myers J, Aslam S, Varughese E, Peberdy M. Influence of subject effort on the prognostic value of peak VO2 and VE/VCO2 slope in patients with heart failure. Journal of Cardiopulmonary Rehabilitation. 2004;24:317-320.
Arena R, Myers J, Aslam S, Varughese E, Peberdy M. Prognostic comparison of the VE/VCO2 ratio and slope in patients with heart failure. Heart Drug.2004;4:133-139.
Arena R, Myers J, Aslam S, Varughese E, Peberdy M. Peak VO2 and VE/VCO2 slope in patients with heart failure: A prognostic comparison. American Heart Journal. 2004;147:354-360.
Arena R, Humphrey R, Peberdy M. Prognostic ability of VE/VCO2 slope calculations using different exercise test time intervals in subjects with heart failure. European Journal of Cardiovascular Prevention and Rehabilitation. 2003;10:463-468.
Arena R, Greenspan N, Tevald M, Haas JE. Safety and efficacy of pulmonary rehabilitation in elderly females with chronic obstructive pulmonary disease: a pilot report. Journal of Cardiopulmonary Physical Therapy. 2003;14:3-6.
Arena R, Myers J, Aslam S, Varughese E, Peberdy M. Technical considerations related to the VE/VCO2 slope in patients with heart failure. Chest. 2003;124:720-727.
Arena R, Humphrey R, Peberdy M, Madigan M. Predicting peak oxygen consumption during a conservative ramping protocol: implications for the heart failure population. Journal of Cardiopulmonary Rehabilitation. 2003;23:183-189.
Arena R, Humphrey R, Peberdy M, Madigan M. Comparison of oxygen uptake on-kinetic calculations during submaximal exercise. Journal of Exercise Physiology. 2003;6:1-7.
Arena R, Humphrey R, Peberdy M, Madigan M. Comparison of oxygen consumption on-kinetic calculations in heart failure. Medicine and Science in Sports and Exercise. 2002;34:1563-1569.
Arena R, Humphrey R, Peberdy M. Relationship between the Minnesota Living With Heart Failure Questionnaire and key ventilatory expired gas measures during exercise testing in patients with heart failure. Journal of Cardiopulmonary Rehabilitation. 2002;22:272-277.
Arena R, Humphrey R, Peberdy M. Using the Duke Activity Status Index in heart failure. Journal of Cardiopulmonary Rehabilitation. 2002;22:23-25.
Arena R, Humphrey R. Comparison of ventilatory expired gas parameters used to predict hospitalization in patients with heart failure. American Heart Journal. 2002;143:427-432.
Arena R, Humphrey R. Measurement of oxygen consumption on-kinetics during exercise: implications for the patient with chronic heart failure. Journal of Cardiac Failure. 2001;7:302-311.
Arena R, Humphrey R. Relationship between ventilatory expired gas and cardiac parameters during symptom-limited exercise testing in patients with chronic heart failure. Journal of Cardiopulmonary Rehabilitation. 2001;21:130-134.
Arena R, Humphrey R. Characteristic expired gas values in heart failure patients during exercise testing. Clinical Exercise Physiology. 2001;3:17-26.
Arena R, Humphrey R, Peberdy M. Safety and efficacy of exercise training in a heart failure patient awaiting heart transplantation while on positive intravenous inotropic support. Journal of Cardiopulmonary Rehabilitation. 2000;20:259-261.
Arena R, Humphrey R. Oxygen uptake kinetics and functional status issues in congestive heart failure: a pilot report. Cardiopulmonary Physical Therapy Journal. 2000;11:54-58.
Humphrey R, Arena R. Update: Surgical advances in heart failure and implications for cardiopulmonary rehabilitation. Physical Therapy. 2000;80:61-69.
Arena R, Humphrey R, McCall R. Altered exercise pulmonary function following left ventricular device implantation. Journal of Cardiopulmonary Rehabilitation. 1999;19:344-346.
Grant funding
The effect of a five week electrical myostimulation program in patients with heart failure.
Principal investigator. A.D. Williams Grant, Virginia Commonwealth University, 2007.
Global function for a rare disease gene: clinical significance of the regulation of
mitochondrial respiration by tumor suppressor p53 in Li-Fraumeni syndrome. Co-
investigator. Collaborative NIH Intramural-Extramural Investigations, 2006.
Effect of aerobic exercise training on arterial stiffness in patients with heart failure. General Clinical Research Center, Virginia Commonwealth University, 2006.
Effects of endurance exercise on bio-behavioral outcomes of fatigue in subjects with breast cancer. Paid consultant. National Institutes of Health, 2005.
Short-term reliability of oxygen uptake kinetics. Principal investigator. The Steinhardt School of Education, New York University, 2002.
Short-term reliability of oxygen uptake kinetics. Principal investigator. A.D. Williams Grant, Virginia Commonwealth University, 2002.
Enhancing the Instruction of ECG Analysis via Real Time Simulation. Principal investigator. Center for Teaching Excellence, New York University, 2001.
Key professional service activities
Board of Directors, American Association of Cardiovascular and Pulmonary Rehabilitation (2005-2007)
Chair of Ethics and Professional Conduct Committee, American College of Sports Medicine (2007)
Associate Editor, Medicine and Science in Sports and Exercise (2005-present)
Editorial Board Member, Journal of Cardiopulmonary Rehabilitation and Prevention (2003-present)
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