Edward R. Bowman, Ph.D.
Dr. Edward R. Bowman, Ph.D., Research Associate of Pharmacology and
Toxicology, passed away on January 26th, 2008. He is survived by his
wife of 53 years, Wilma; his daughter, Gay Bowman; brothers, William
Bowman, Lance Bowman, and Garland Bowman; and sisters, Elizabeth Woody,
Barbara Fogus, and Mary Shrader. Dr. Bowman was a US Army veteran and
served in both World War II and the Korean War. After earning his
bachelor's degree at Concord College in biology and chemistry, Dr.
Bowman completed a master's degree in physiology at West Virginia
In the spring of 1956, he came to VCU as a research assistant to our
Department and completed his doctoral degree in pharmacology in 1963.
Since then, he has served on the Pharmacology and Toxicology faculty as
a Research Associate.
In his career, he has dedicated a quarter-century to the study of the
metabolism of nicotine in several mammalian species, including man. An
especially notable contribution was his discovery of a simple, elegant
and direct method for the synthesis of stereoisomers of nicotine. As
pioneers in this field, he and his coworkers were the first to identify
at least 10 metabolites of nicotine without the aid of some of the more
modern instrumentation available today.
Since 1985, on behalf of the National Institute on Drug Abuse and the
College on Problems of Drug Dependence (CPDD), he was involved in the
evaluation of over 500 compounds for their abuse liability. He has
participated in preclinical studies in nonhuman primates on the duration
of action and efficacy of depot preparations of naltrexone and
buprenorphine. Comparable preparations are now used in the therapy of
human opioid abuse.
As his research has progressed, he has authored or co-authored some 160
articles on his findings in some of the scientific field's leading
publications. He belonged to several professional societies, including
the American Chemical Society, American Society of Pharmacology and
Experimental Therapeutics, and Society for Experimental Biology and
Medicine. In addition to his research interests, Dr. Bowman has also
participated in teaching in the schools of Pharmacy, Dentistry and
Medicine. Ed, as he was called, was an unassuming and witty man. Above
all, he was a gentleman. He will be missed.
Dr. Bowman, Wilma and daughter, Gay