Associate Professor of Anatomy and Neurobiology
Degree: Ph.D., Virginia Commonwealth University
Identification of factors that mediate neuron-oligodendrocyte interactions in
the adult nervous system; determining the consequences that result when these cell-cell communications
are disrupted. Our recent work indicates that a specific oligodendrocyte lipid, sulfatide, is required for the
maintenance of neuron-oligodendrocyte interactions and for proper neuronal function and viability.
Since recent clinical findings show that a significant sulfatide reduction is an early and consistent
finding in several forms of dementia including Alzheimer's disease, our work may provide important
insight into the pathogenesis of human neurodegenerative disease.