John M. Kellum, MD
Chair, Division of General Surgery
Professor, VCU Dept of Surgery
Laparoscopic Surgeon

Address:
P.O. Box 980519, Richmond, VA 23298-0519

Principal hospital base:
VCU Medical Center

Current professional and academic appointments:
Professor of Surgery, 1983

Undergraduate and medical education:
Emory University, Atlanta, Georgia, 1962 - 1964
Johns Hopkins University School of Medicine, Baltimore, Maryland, B.A., 1966
Johns Hopkins University School of Medicine, Baltimore, Maryland, M.D., 1969

Postgraduate medical education:
Senior Assistant Resident, Surgery, Barnes Hospital, St. Louis, Missouri, 1971-1973
Chief Resident, Surgery, Barnes Hospital, St. Louis, Missouri, 1973-1974
Fellow, Surgical Research, Washington University School of Medicine (Bernard M. Jaffe, M.D., Preceptor), St. Louis, Missouri, 1974-1975

Licensure:
Virginia, Maryland, Missouri, Massachusetts

Role in residency program:
Dr. Kellum participates in clinical teaching of PGYs I-V in and out of the operating room, in addition to offering research opportunities in gastrointestinal physiology.

Research interests:
This laboratory is engaged in NIH-funded research into the role of 5-hydroxytryptamine (5-HT) in regulating intestinal transport of water and electrolytes. Since 5-HT and its receptors are present both on intestinal enterocytes and on enteric neurons, both mucosal and neural physiology are important. One model now being pursued is an in vitro model of intestinal obstruction. The early results suggest that serotonin receptors on enteric sensory nerves partly mediate the secretory changes seen when the intestinal mucosa is subjected to increased luminal pressure. We have the advantage of a unique availability of normal human jejunal segments, harvested during gastric bypass operations, for study.

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