The long-term goal of this project is to apply novel mathematical and computational modeling technologies, well informed by biological experimentation, to specific host-parasite systems in order to develop new paradigms for understanding the infectious disease process, for the purpose of developing new therapeutic and public health interventions and strategies. Towards these goals, we will develop, use, and make available an extensible, portable, in silico, multi-scale, high performance computational laboratory for the study of parasite-host dynamics and use that model to study effective strategies for managing the host-vector and parasite dynamics of the T. cruzi parasite, the causal agent in Chagas’ Disease.

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