Program



Tuesday, June 16th

5:00 PM         Registration Open at Omni Hotel, Dinner on Your Own

9:00 PM         Registration Closes at the Omni Hotel



Wednesday, June 17

7:30 AM         Continental Breakfast and Registration Open

8:45 AM         Welcoming Remarks

Session I: Microbial Engineering [Chair: Steve Fong]

9:00 AM         Plenary Speaker: Kristala Prather, MIT:

Rational Design of Microbial Chemical Factories

10:00 AM       Jingdong Tian, Duke University:

Enabling Effective Design, Construction and Optimization of Synthetic Biosystems

10:25 AM       Break

10:35 AM       Hao Song, Duke University:

Spatiotemporal Modulation of Biodiversity in a Synthetic Chemical-Mediated Ecosystem

11:00 AM       Plenary Speaker: Christina Smolke, Stanford University:

Advancing Synthetic Metabolic Network Design Through Embedded Sensing-Actuation Devices

12:00 PM       Lunch Provided at the Omni Hotel

1:00 PM         Keynote Speaker: James Collins, Boston University:

Engineering Microbial Gene Networks: Integrating Synthetic Biology and Systems Biology

Session II: Modeling Microbial Systems [Chair: Hao Song]

2:00 PM         Plenary Speaker: Jean Peccoud, Virginia Tech:

An Engineering Approach to Characterizing Structure-Function Relationship in DNA Sequences

3:00 PM         Break

3:15 PM         Christopher Gowen, VCU:

Genome-Scale Constraint-Based Metabolic Models as Tools for Engineering Cellulosic Biofuel Production

3:40 PM         Paul Jensen, UVA:

Systems Approaches to Infectious Disease

4:05 PM         Seth Roberts, VCU:

Proteomic and Network Analysis Characterize Stage-Specific Metabolism in Trypanosoma cruzi

4:30 PM         Ping Xu, VCU:

Biofilm Gene Association in Oral Streptococci by Systems Biology

6:30 PM         Banquet Dinner at the Omni Hotel



Thursday, June 18

7:30 AM         Continental Breakfast

Session IIIa: Host-Pathogen Interactions [Chair: Dennis Ohman]

8:30 AM         Plenary Speaker: James Musser, The Methodist Hospital, Houston, Texas:

New Understanding of Group A Streptococcus Pathogenesis Provided by Integrated Systems Biology Studies

9:30 AM         Candice Johnson, Meharry Medical College:

Gene Network Analysis During Early Cellular Infection by Trypanosoma cruzi

9:55 AM         Shlomo Ta'asan, Carnegie Mellon University:

A Mathematical Approach for Understanding Host-Pathogen Interactions

10:20 AM       Break

10:35 AM       Plenary Speaker: Cammie Lesser, Harvard University:

Yeast Functional Genomic Approaches Provide New Insights into How Human Bacterial Pathogens Cause Disease

11:35 AM       Alison Criss, University of Virginia:

Disarming of Host Neutrophil Defenses by Neisseria gonorrhoeae

12:00 PM       Lunch Provided at the Omni Hotel

Session IIIb: Host-Pathogen Interactions [Chair: Patricio Manque]

1:00 PM         Isabel Santos, University of São Paulo-Riberão Preto, Brazil:

Transcriptional Profiles of Tick-Infested Skin and Tick Salivary Glands in Contrasting Phenotypes of Tick-Host Interfaces Reveal Patterns that are Associated with Resistance to Ticks

1:25 PM         Judith Klein-Seetharaman, Carnegie Mellon University:

Identification of Alternative Routes Circumventing HIV-1 Targeted Pathways in Human Signal Transduction Networks

1:50 PM         Keynote Speaker: David Botstein, Princeton University:

Coordination of Growth Rate, Cell Cycle, Stress Response and Metabolic Activity in Yeast

2:50 PM         Break

Session IV: Human Microbiome [Chair: Patrick Gillevet]

3:05 PM         Plenary Speaker: Jeremy Nicholson, Imperial College London:

Top-Down Systems Biology of Metabolic Supersystems: From Personalized Healthcare to Molecular Epidemiology

4:05 PM         Patrick Gillevet, George Mason University:

The Human Metabiome: Correlating the Human Microbiome with Disease

4:30 PM         Huzefa Rangwala, George Mason University:

Disease Inference Using Microbiome Informatics

5:00 PM         Plenary Speaker: Michelle Giglio, University of Maryland:

A Data Analysis and Coordination Center for the Human Microbiome Project

6:00 PM         Heavy hors d'ouevres and Poster Session

Technology Workshop [Chair: Sheryl Baldwin]

7:15 PM         Tim Harkins, Roche Corporation:

Genome Analysis for the Tree of Life

7:45 PM         Iggy Kaas, Waters Corporation:

Chemical Intelligence and Accurate Mass of Precursor and Product Ions: How They Combine to Maximize Information Content in Complex Biological Analyses

8:10 PM         Charles Cochran, Applied Biosystems:

SOLiD 3 System and Beyond

8:35 PM         Doug Phanstiel, University of Wisconsin:

Comparing Human ES, iPS, and Somatic Cells Using iTRAQ and Beam-type CAD with Ion Trap Mass Analysis



Friday, June 19

7:30 AM         Continental Breakfast

Session V: Technological Advances in Systems Biology [Chair: Paul Fawcett]

8:30 AM         Plenary Speaker: Yuan Gao, VCU:

Transforming Basic and Translational Research by Next-Generation Sequencing

9:30 AM         David Williamson, Illumina:

Assembling and Visualizing Small Genomes Using Pooled and Indexed Samples

9:55 AM         Dan Sullivan, Virginia Tech:

Data Integration for Dynamic and Sustainable Systems Biology Resources: Challenges and Lessons

10:20 AM       Break

10:35 AM       Keynote Speaker: John Yates, Scripps Institute:

Driving Biological Discovery Using Quantitative Mass Spectrometry

11:35 AM       Closing Remarks

11:40 PM       Lunch Provided at the Omni Hotel

1:00 PM         Workshops

Workshop 1: The Microbial Tree of Life [Chair: Maria Rivera]

1:00 PM         Mark Farmer, University of Georgia:

Re-rooting the Tree of Life

1:40 PM         Richard Triemer, Michigan State University:

Phylogeny of Photosynthetic Euglenoids – What Have We Learned?

2:20 PM         Break

2:40 PM         Maria Rivera, VCU:

The Euglenozoa Tree of Life: Avoiding Phylogenetic Artefacts in Genome-Scale Analyses

3:10 PM         João M. Alves, VCU:

Challenges in Climbing the Tree of Life

3:40 PM         Danail Bonchev, VCU:

Evolution of Metabolic Networks Organization

4:10 PM         Jeff Elhai, VCU:

Biobike: Providing Biologists without Programming Experience Creative Control over the Analysis of Bioinformation

Workshop 2: Gene Networks and Disease [Chair: Zhongming Zhao]

1:00 PM         Plenary Speaker: Mark Gerstein, Yale University:

Understanding Protein Function on a Genome-scale Using Networks

2:00 PM         Bing Zhang, Vanderbilt University:

Network Approaches to Elucidate the Molecular Basis of Disease

2:25 PM         Victor Jin, Ohio State University:

Dissecting Hierarchical Regulatory Network of Estrogen-Dependent Breast Cancer through an Integrative Genomic Analysis

2:50 PM         Break

3:05 PM         Soumya Raychaudhuri, Broad Institute:

A Text-Based Strategy to Identify Disease Variants: Looking for Gene Relationships Across Implicated Loci (GRAIL)

3:30 PM         Nathan Menke, VCU:

Fuzzy Modularity of Biological Networks

3:55 PM         Ali Abdi, New Jersey Institute of Technology:

Fault Diagnosis Engineering in Molecular Signaling Networks

4:20 PM         Jingchun Sun, VCU:

A Comparative Study of Schizophrenia and Cancer Gene Network Properties