Program

Monday, June 4
Welcome Reception with VA Bio Networking, Jefferson Hotel
6:00-9:00
Registration, Jefferson Hotel
6:00-9:00
Welcome Reception and VaBio After Hours
Tuesday, June 5    
7:00-8:00
Registration/Continental Breakfast
8:00-8:10
Conference Welcome: Dr. Eugene P. Trani, President/VCU
Session I: The Systems Biology Challenge in 21st Century Biomedical Research
 
Session Chair: Leroy Hood, President, Institute for Systems Biology
8:10-9:00
Keynote Lecture- Leroy Hood: Systems Approaches in Biology and Medicine  
9:00-9:15
Claire Fraser-Liggett: Perspectives on Systems Biology from the Research Institute  
9:15-9:30
David Balshaw: Perspectives on Systems Biology from the NIH  
9:30-10:00
Michael Savageau: Perspectives on Systems Biology from Academia  
10:00-10:15
Break  
10:15-10:30
Burt Adelman: Perspectives on Systems Biology from the Pharmaceutical Industry  
10:30-11:00
Keith Elliston: Systems Pharmacology: An Application of Systems Biology  
11:00-12:15
Panel Discussion: Systems Biology: What is it, why do it, and will it work?  
Moderator: Leroy Hood  
12:15-1:30
Lunch
Session II: Complexity in Cellular and Sub-cellular Systems: from molecules
 
Session Chair: Richard Summers, University of Mississippi
1:30-2:20
Session Keynote: Claire Fraser-Liggett, University of Maryland  
Human Microbial Metagenomics – Understanding Our Microbial Selves  
2:20-3:10
Rene Thomas, Universite Libre de Bruxelles  
Circular Causality: Principles for the analysis and synthesis of dynamical systems  
3:10-3:30
Break  
3:30-4:20
Masaru Tomita, Keio University  
Multi-omics analysis and data-driven systems biology, E-cell  
4:20-5:10
Christoph Adami, California Institute of Technology
Digital Genetics: Unraveling the Genetic Basis of Evolution
5:30-7:00
Reception and Student Posters
Heavy hors d'oeuvres and open bar
Special Event
 
7:00-8:30
Student Research Symposium
     
Wednesday, June 6
7:00-8:00
Registration/Continental Breakfast
Session III: Pathways and Networks in Basic Research
 
Session Chair: Paul Fawcett, Virginia Commonwealth University
8:00-8:50
Session Keynote: Bernhard Palsson, University of California-San Diego  
Metabolic Modeling  
8:50-9:40
George Church, Harvard University  
Genome Design, Engineering, & Evolution in Cell Cultures  
9:40-10:20
Break  
10:20-11:10
Michael Savageau, University of California-Davis  
Function, Design and Evolution of Gene Circuitry  
11:10-12:00
Marc Vidal, Center for Cancer Systems Biology  
DFCI and Harvard Medical School Interactome Networks  
12:00-1:00
Lunch
Session IV: Systems Biology in Clinical and Translational Research I
 
Session Chair: Robert Gerszten, Harvard Medical School
8:00-8:50
Session Keynote: James Bassingthwaighte, University of Washington
Multiscale Modeling of the Heart, from Metabolism to Cardiac Output
8:50-9:40
Joe Loscalzo, Harvard University
Systems Biomedicine and Human Disease: A New Approach to Pathobiology and
  Therapeutics  
9:40-10:20
Break
10:20-11:10
Gilles Clermont, University of Pittsburgh
Modeling Critical Illness
11:10-12:00
Thomas E. Johnson, University of Colorado
Genetics of Aging in C. elegans
12:00-1:00
Lunch
Session V: Systems Biology in Clinical and Translational Research II
 
Session Chair: Tom Skalak, University of Virginia
1:00-1:50
Session Keynote: Bruce West, Army Research Office  
Where Medicine Went Wrong  
1:50-2:40
Robert Gerszten, Harvard Medical School  
Metabolomics of Planned Heart Attacks  
2:40-3:10
Break  
3:10-4:00
Raimond L. Winslow, Johns Hopkins University School of Medicine  
Integrative Modeling of Cardiac Function in Health and Disease  
Conference Keynote:    
4:00-5:00
Stuart Kauffman, University of Calgary  
All Cells are Dynamically Critical  
6:00 – 9:00
Gala Dinner at the Virginia Museum of Fine Arts  
  Music By: VCU Jazz Trio  
     
Thursday, June 7      
7:00-8:00
Registration/Continental Breakfast
Session VI: Systems Immunology and Oncology
 
Session Chair: Chip Petricoin, George Mason University
8:00-8:50
Martin Meier-Schellersheim, NIAID  
An integrated approach to computational Systems Biology: from bimolecular  
  interactions to the behavior of multi-cellular systems  
8:50-9:40

Joe Nevins, Duke University

Genomic Strategies for Personalized Cancer Therapy  
Closing comments: Gregory A. Buck, Virginia Commonwealth University  
  Chair of the Summit Steering Committee  
9:40-10:10
Coffee Break/Registration for workshops
Modeling Workshops (all invited for AM lectures; separate registration for PM sessions)
 
Session Chair: Kevin Ward, Virginia Commonwealth University
10:10-11:00
Tarynn M. Witten, Virginia Commonwealth University  
Overview of Modeling Complex Biomedical Systems  
11:00-11:50
Richard Summers, University of Mississippi  
Approaches to Modeling in Basic, Clinical and Translational Research  
12:00-12:15
Vans to Trani Center for Life Sciences  
12:15-1:00
Lunch, VCU Life Sciences Conference Room and the Atrium
Hands-on Workshops (Virginia Commonwealth University)
1:00-6:00
Workshop I, Fast Start Modeling and Simulation Tools
for Basic Biological Research
1:00-6:00
Workshop II, Modeling and Simulation
of Organ Systems for Clinical Researchers