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------------------------------------- Gary Berg-Cross, Ph.D. Gary Berg-Cross, Ph.D.
More information: www.nih-bcig.org.
Daniel B. Carr, Ph.D. VCU Statistics Faculty Research Seminar "Some New Graphics for Visualizing Statistics Indexed by Nucleotide and Amino Acid Letter Sequences" This presentation concerns the development of a new methodology for visualizing statistics indexed by nucleotide or amino acid letter sequences. The talk presents three contexts that give rise to letter-indexed statistics: the study of gene regulation docking sites, peptide docking on human immune system molecules and the application of computational geometry to characterize protein structure and protein families. Published representation of letter-indexed statistics often consists of a table, sorted by one column and clipped to show a small number of items. The approach here constructs 2-D and 3-D coordinates based on the letters sequences, uses glyphs to represent statistics and easily accommodates a few thousand items. Software called GLISTEN (geometric letter-indexed statistical table encoding) provides 3-D rendering, GIS-like layering and selective focus via pan, zoom and filtering. Continuing challenges include incorporating more scientific structure in the construction of coordinates and enhancing the GUI (graphical user interface) to enable easier sequential removal of the currently dominant visual structure. Refreshments will be served at 2:30 p.m. in Sanger Hall,
B1-066-A. Dr. Lowell H. Hall Dr. Lowell H. Hall "The Role of the Electrotopological State in Modeling Biological Properties"
Presented by Tristan Gill in
California via web
Most of you have seen their claims about fast processing. Please mark your calendars and come if you can. Bring anyone else who might have interest. Click HERE for Paracell's Paracel Information Packet/Presentation Agenda.
|| Thursday October 16, 2003|| Frank Hartel, Ph.D. Frank Hartel, Ph.D.
NCI Thesaurus is a cancer research nomenclature with ontology-like features. The Thesaurus is created by the NCI Center for Bioinformatics and the Office of Cancer Communications for the use of the Institute and the cancer research community. The Thesaurus serves several functions, including annotation of data as it is stored in the Institute's repositories, and search and retrieval operations against the repositories. Concept-level history is critical for satisfactory search and retrieval. The annotations in the repositories are static, but the Thesaurus evolves rapidly, reflecting the pace of discovery in cancer research. I will describe the algorithms and software methods used to capture changes to the content of the Thesaurus that occur during the update/build cycle, the resulting concept history data structure, the API that provides access to the concept history in our vocabulary server environment, and examples of how concept-level history improves search and retrieva Bio Frank Hartel received MS and PhD degrees in experimental psychology from the Illinois Institute or Technology where he focused on cognitive processes and linguistics. He was a postdoctoral fellow in psychiatry at the University of Chicago where he learned the basics of biomedical computing in drug research. Subsequent experience as a computer scientist at the US Army Research Institute and as a member of the technical staff at the MITRE Corporation broadened his experience to include human performance assessment and human-computer interaction and designing systems that support human performance in information-intensive and cognitively challenging applications. After a brief period as director of a computational biology program at the National Science Foundation, Dr. Hartel moved to the National Institutes of Health where he was the senior NIH information resources manager. Moving back into applied research, Dr. Hartel has, for the last six years, been director of the National Cancer Institute's Enterprise Vocabulary Systems project (NCI EVS). The NCI EVS is a component of the Institute's Center for Bioinformatics (http://ncicb.nci.nih.gov) caCORE. Dr. Hartel serves as the coordinator and project officer for efforts related to Institute-level vocabulary development, as well as for collaborations between NCI and other government agencies and non-governmental organizations that are interested in biomedical vocabulary. Refreshments will be served. More information: www.nih-bcig.org.
Peter Moore. Structural Biology Seminar: Professor Peter Moore. To learn more about Professor Moore go to: http://proton.chem.yale.edu/ This Special Seminar is sponsored by the Department of Biochemistry, Medicinal Chemistry and the University of Richmond
|| Wednesday October 24, 2003|| Dr. Stephen W. Kercel Dr. Stephen W. Kercel
John Bander, M.S. VIRGINIA COMMONWEALTH UNIVERSITY John Bander, M.S. Abstract: Microarray technology is having an enormous impact across the agricultural, biotechnology and pharmaceutical industries. These experiments generate large quantities of complex data. As the field matures, the analyses are shifting from ad hoc to rigorous and statistical. We will discuss some of the statistical challenges and present an analysis of some lung cancer data. The analysis will be performed with SASŪ Microarray Solution which provides data management, analysis and visualization tools specific to microarray analysis.
Refreshments will be served at 2:30 p.m. in Sanger Hall,
B1-066-A.
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