| BNFO 601 |
Course at a Glance : List of topics |
Fall 2010
|
| Scientific Problem | Bioinformatic Tool | |
| IntP | Introduction to Perl | Personal programming |
| IntM | Introduction to molecular biology | Essential
biology for bioinformatics students |
| 1 | Comparison of genomes of pathogenic and nonpathogenic bacteria, looking for genes responsible for pathogenesis | Parsing programs |
| 2 | Identification of a possible regulatory site in genomic DNA | Simple simulations, Pattern search programs |
| 3 | Alignment of mystery sequence with known anthrax toxins | Sequence alignment |
| 4 | Search for set of genes with common regulation | Position-specific probability matrices |
| 5 | Analysis of a biochemical pathway in order to determine the best site to target a drug | Metabolic modeling |
| 6 | Determination of genes turned on during
a developmental cascade |
Heirarchical
cluster analysis |
| 7 | Prediction of structure of protein of industrial importance | Molecular threading |
| 8 | Identification of genes of foreign origin | Markov models |