Integrated Bioinformatics (Fall 2008)
Questionnaire on notes: Modeling - Introducing Inhibition
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I. Basic Information

A. Your name 
II. Retrospective on problems with glycolysis
A.  How far are you along in getting [NAD] and [NADH] to change over the course of the simulation?
 
B.  How far are you along in introducing DHAP metablism (the left hand side of Figure 1) into your program?
 
C.  Do you have any obstacles in working with the program that warrants discussion?
 
Responses to questions in Section II:
III. Problem with separate compartments
A.  Do you have a good idea of what the subroutine Calculate_AXP is trying to do?
 
B.  Do you have a good idea of how the subroutine Calculate_AXP works?
 
C.  Do you have a good idea of how to change the subroutine Calculate_AXP so that it maintains the conserved pools? Have you made progress on this?
 
Responses to questions in Section III:


Please choose up to three study questions from the notes that you would most like discussed in class:
SQ1  SQ2  SQ3  SQ4  SQ5  SQ6  SQ7 
IV. Inhibition of individual steps of glycolysis
A.  Any problems understanding Equation 8?
 
B.  Any problems implementing Equation 8 into your program?
 
C.  Do you recall (perhaps from the first set of notes) the difference between competitive and uncompetitive inhibition?
 
Responses to questions in Section IV:


Please choose up to three study questions from the notes that you would most like discussed in class:
SQ8  SQ9  SQ10  SQ11  SQ12 
V. Miscellaneous

Any miscellaneous comments, questions, suggestions, concerns?

Thanks!

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