VCU Bioinformatics and Bioengineering Summer Institute
Virginia Commonwealth University

Shozo Ozaki
  Sanger Hall, Room 5-036
  Dept. of Microbiology and Immunology
  Virginia Commonwealth University
  Richmond VA 23284-0678
Tel: 804-828-2318
Fax: 804-828-9946
  Research: Comparison of expressed genes amongst pathogenic protozoan parasites

BBSI project:Identification of genes related to different life styles of kinetoplastids
Kinetoplastids are protozoa within the family Trypanosomatidae with a wide range of medical, agricultural, and veterinary importance. Trypanosoma brucei, the causative agent of sleeping sickness, is one member of this group. I am interested in determining the pattern of gene expression in kinetoplastids with similar modes of infection (e.g. by insect bite) or similar life styles (e.g. intracellular). Such a global comparative study of transcription may shed light on the mechanisms underlying particular complex behaviors.

Useful articles
Gibbs RA, Nelson DL (2003). Primate shadow play. Science 299:1331-1332

Bofelli D et al (2003). Phylogenetic shadowing of primate sequences to find functional regions of the human genome. Science 299:1391-1394

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