Virginia Commonwealth University

Laboratory of Paul M. Fawcett

Paul Fawcett, Ph.D., Assistant Professor
Department of Internal Medicine, Division of Infectious Disease and Center for the Study of Biological Complexity

 

Mouse Macrophage infected with Listeria monocytogenes

UCSF/Stanford design Mark III microarrayer

Innate immunity signalling pathways

Clustergram of microarray data


 

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The Fawcett lab maintains and develops:

  • The Ramhorn Microarray Database (RAD), a VCU-specific localization and extension of the open-source Longhorn Array Database (LAD), which seamlessly integrates the functionality of the Significance Analysis of Microarrays (SAM) package.  
  • A custom home-built Stanford / UCSF-design "MarkIII" 48-pin high-speed microarrayer, which is used to produce numerous microarrays, including the VCU mouse microarray, a MEEBO-compliant whole genome spotted oligonucleotide microarray.
  • SLEDRIDE (Supervised Learning of Expression Data in a Desktop Environment). Currently under active development, SLEDRIDE is an open source platform-independent software package implemented in Java for the analysis and visual exploration of microarray gene expression data. SLEDRIDE replaces and greatly extends the functionality of DECCOR2, which is now obsolete.




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