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The members of the Cholesterol/ Liver Function Group, Drs. Peterson, Gil, Grogan, Dent, and Barbour are using biochemical and structural approaches to further understand the functioning of the liver in health and disease. Their research interests are largely focused on cholesterol and lipoprotein metabolism. With their combined expertise in lipid hydrolase enzymology, lipoprotein composition and function, and the regulation of gene expression by cholesterol and other sterols, this group hopes to develop a more comprehensive picture of lipid metabolism in the liver. Such information will be useful for the design and implementation of novel treatments of diseases that affect the liver and/ or are impacted by liver function.
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Darrell Peterson, Professor:
Structure and function of proteins
of hepadnaviruses and hepatitis C virus.
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Gregorio Gil, Associate Professor:
Molecular mechanisms of
cholesterol and bile acid regulation of gene expression.
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W. McLean Grogan, Professor:
Properties and regulation of
cholesteryl ester hydrolases; cholesterol metabolism.
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Suzanne Barbour, Professor:
Role of PLA2 and lipid
mediators in the regulation of sterol metabolism.
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Paul Dent, Professor:
Signaling processes regulating
survival of liver cells.
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1101 E Marshall St | PO Box 980614 | Richmond, VA 23298 | ph 804.828.9762 | fax 804.828.1473
Site Update July 20, 2008, Responsible Unit - Department of Biochemistry & Molecular Biology, biochemgrad@mail.vcu.edu
Virginia Commonwealth University,
VCU School of Medicine
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