A. D. Williams Research grants

"A Pilot Study of Platelet Structure and Function in Dialysis Patients."
Dr. Donald Brophy, Associate Professor of Pharmacy, was awarded $14,952: $10,717 from the Harvell Foundation Trust Funds and $3,875 from A.D. Williams Trust Funds.

"Post-Ischemic Myocardial Angiogenesis by Prolyl Hydroxylase Inhibition."
Dr. Ramesh Natarajan, Assistant Professor of Internal Medicine, was awarded $15,000 from the Crump Foundation Trust Funds.

APRIL, 2009 AWARDS:

A. D. Williams Research grants

"Role of /Star /Proteins in Intracellular Cholesterol Metabolism."
Dr. Daniel Rodriguez-Agudo, Assistant Professor of Internal Medicine, (Division of Gastroenterology, Hepatology and Nutrition), was awarded $15,000 from the Staton Heart Fund Foundation Trust Funds.

"Evaluation of Genetic Biomarkers of Aminoglycoside-Induced Kidney Injury in Newborn Infants."
Dr. Mary Jayne Kennedy, Assistant Professor of Pharmacy, was awarded $14,500: $2,900 from the Blanton Foundation Trust Funds, $6,500 from the Friel Foundation Trust Funds and the balance of $5,100 from the A. D. Williams Trust Funds.

"Attenuation of post-AMI Inflammation through Pharmacologic MyD88 Inhibition."
Dr. Benjamin Van Tassel, Assistant Professor of Pharmacy, was awarded $15,000: $6,500 from the Staton Heart Fund Foundation Trust and $8,500 from the Crump Research Trust Funds.

"Novel Roles for Collagen XVIII in CNS Synapse Formation."
Dr. Michael A. Fox, Assistant Professor of Anatomy & Neurobiology, was awarded $15,000 from the A. D. Williams Trust Funds.

"Mobilization of Staphylococcal Superantigen Pathogenicity Islands."
Dr. Gail E. Christie, Professor of Microbiology & Immunology, was awarded $25,000. This is a bridge award: $9,000 from the Baruch Foundation Trust Funds and the balance of $16,000 from the A. D. Williams Trust Funds.

A. D. Williams Multidisciplinary Research Grant

"Molecular Modeling and Bio-array Based Novel Anti Prostate Cancer Drug Discovery."
Dr. Yan Zhang, Assistant Professor of Medicinal Chemistry, is the Prinipal Investigator on this research grant awarded $125,186 from the A. D. Williams Trust Funds.

A. D. Williams Research grant

"Mechanism and Regulation of Vitamin B6 Metabolism."
Dr. Martin K. Safo, Assistant Professor of Medicinal Chemistry, was awarded $15,000 from the A. D. Williams Trust Finds.

OCTOBER, 2008 AWARDS

"SOS Mediated ß-lactam Response and Development of Homogeneous Expression of Resistance in Methicillin Resistant S. aureus Clinical Isolates."
Dr. Adriana E. Rosato, Assistant Professor of Internal Medicine (Infectious Diseases), was awarded $15,000 from the Medical Research Endowment Trust Funds.

"Role of Toll-Like Receptors in Mediating an Innate Immune Response in Astrocytes following Treatment with Opioid Agonists and HIV Viral Proteins."
Dr. Nazira El-Hage, Assistant Professor of Pharmacology & Toxicology, was awarded $15,000 from the A. D. Williams Trust Finds.

JULY, 2008 AWARDS

"Quinazolines: Potential Analgesic Adjuvants."
Dr. Malgorzata Dukat , Associate Professor of Medicinal Chemistry, was awarded $15,000 from the A. D. Williams Trust Funds.

"A Mechanistic Role for Prostaglandins in Overactive Bladder: Does Spontaneous Detrusor Activity Arise from Interstitial Cell to Detrusor Smooth Muscle Signaling?"
Dr. Adam P. Klausner, Associate Professor of Urology, was awarded $15,000: $8,500 from the Blanton Trust Funds and $6,500 from the A. D. Williams Trust Funds.

"Bifunctional Ligands as Novel Amyloid-beta Oligomerization Inhibitors."
Dr. Shijun Zhang, Assistant Professor of Medicinal Chemistry, was awarded $15,000 from the A. D. Williams Trust Funds.

"The Effect of Training on a Modified Elliptical Device on Functional Mobility in a Hemiparetic Population."
Dr. Peter E. Pidcoe, Associate Professor of Physical Therapy, was awarded $14,869 from the A. D. Williams Trust Funds.

"Role of microRNAs (miRs) in Prostate Tumor Progression."
Dr. Zendra Zehner, Professor of Biochemistry & Molecular Biology, was awarded $25,000. This is a "bridge" application provided by the A. D. Williams Trust Funds.

"Dystonia in an Animal Model of Kernicterus."
Dr. Steven M. Shapiro, Associate Professor of Neurology, was awarded $25,000. This is a "bridge" application provided by the A. D. Williams Trust Funds.

"Preventing Post-infarction Remodeling by Inhibiting Interleukin-1 with Anakinra: The Anakinra Remodeling Trial (ART)."
Dr. Antonio Abbate, Assistant Professor of Internal Medicine, Division of Cardiology, was awarded $14,975 from the A. D. Williams Trust Funds.

"A Novel Genetic Model for Investigating Mechanisms of Wolfram Syndrome."
Dr. Michael S. Grotewiel, Associate Professor of Human and Molecular Genetics, was awarded $15,000 from the A. D. Williams Trust Funds.

"Dual Direct Inhibitors of Thrombin and Factor Xa."
Dr. Umesh R. Desai, Professor of Medicinal Chemistry, is the principal investigator of a multi-school application. $120,000 was awarded in support of that application from the A. D. Williams Trust Funds.

APRIL, 2008 AWARDS:

A. D. Williams Research Grants

"Regulation of Cardiac Chloride Currents by Reactive Oxygen Species."
Dr. Clive M. Baumgarten, Professor of Physiology and Biophysics, was awarded $25,000 from the A. D. Williams Trust Funds.

"The Role of Sterol Carrier Protein 2 (SCP2) and Liver Fatty Acid Binding Protein (FABP1) for Cholesterol Homeostasis."
Dr. Michael Fuchs, Associate Professor of Internal Medicine (Division of Gastroenterology), was awarded $15,000: $7,250 from the Medical Research Endowment Trust Funds and $7,750 from the A. D. Williams Trust Funds.

"Health Psychophysiological and Neuroendocrine Reactivity Patterns in Children with Autism."
Dr. Stacey E. Reynolds, Assistant Professor of Occupational Therapy, was awarded $14,946 from the A. D. Williams Trust Funds.

A. D. Williams Research Grants

"Genome Stability Genes which Acquire a Function in Invasion during Breast Cancer Progression."
Dr. Aylin Rizki, Assistant Professor of Radiation Oncology, was awarded $15,000 from the A. D. Williams Trust Funds.

"Role of Nitric Oxide in Microvascular Oxygen Transport."
Dr. Roland N. Pittman, Professor of Physiology, was awarded $25,000 from the A. D. Williams Trust Funds. This is a bridge application.

"Isolation and Identification of Novel Forms of Neurofascin."
Dr. Jeffrey L. Dupree, Assistant Professor of Anatomy and

"Molecular-genetic Analysis of the Effects of Population Admixture on
Neurobiology, was awarded $14,944 from the A. D. Williams Trust Funds.

"Maintaining Protective Immunity to Trypanosoma Cruzi."
Dr. Ronald B.Smeltz, Assistant Professor of Microbiology and Immunology, was awarded $15,000 from the A. D. Williams Trust Funds.

"Effect of NMDA - Partial Agonists and Histaminergic H3 Antagonists/Inverse Agonists on the Spontaneous Recovery of Aversive Memories."
Dr. Cristina I. Vargas-Irwin, Assistant Professor of Pharmacy, was awarded $14,810 from
the A. D. Williams Trust Funds.

OCTOBER, 2007 AWARDS:

A. D. Williams Research Grants

"Immunostimulatory Effects of DNA from Porhydromonas gingivalis on Human Monocytes."
Dr. Sinem Esra Sahingur, Assistant Professor of Periodontics, was awarded $15,00 from the A. D. Williams Trust Funds.

"Synthesis and Biochemical Characterization of 3rd Generation Rationally Designed Antithrombin Activators."
Dr. Umesh R. Desai, Professor of Medicinal Chemistry, was awarded $25,000: 10,000 from the Harvell Foundation Trust Funds and $15,000 from the A. D. Williams Trust Funds.

"Enhancing Early Detection of Hearing Loss by Newborn Molecular Screening of Common Deafness Genes."
Dr. Arti Pandya, Associate Professor of Human Genetics, was awarded $22,635: $2,635 from the Bayliss Foundation Trust Funds and $20,000 from the A. D. Williams Trust Funds.

"Role of ELR+CXC Chemokine CXCL5 in Tumor Development."
Dr. Hiroshi Miyazaki, Assistant Professor of Oral and Craniofacial Molecular Biology, was awarded $14,999 from the Medical Research Endowment Trust Funds.

"Ligand-Selective Regulation of CB_1 Receptors in Brain."
Dr. Laura Sim-Selley, Associate Professor of Pharmacology and Toxicology, was awarded $24,955: $8,750 from the Baruch Foundation Trust Funds and $16,245 from the A. D. Williams Trust Funds.

"Prevention of Oxidant Induced Apoptosis in Gastric Epithelial Cells by Heat Shock Proteins."
Dr. Thomas A. Miller, Professor of Surgery, was awarded $24,850: $6,300 from the Friel Foundation Trust Funds and $18,550 from the A. D. Williams Trust Funds.


JULY, 2007 AWARDS:

A. D. Williams Research Grants

"Cholesteryl Ester Hydrolysis and Cholesterol Efflux."
Dr. Shobha Ghosh, Associate Professor of Internal Medicine, Division of Pulmonary and Critical Care Medicine, was awarded $25,000 from the A. D. Williams Trust Funds.

"The Validation of a Test-bed Haptic Device for Examining the Utility of New Tactile Graphical Representations for People who are Blind or Visually Impaired."
Dr. Dianne Pawluk, Assistant Professor of Biomedical Engineering, was awarded $14,568: $6,000 from the Friel Foundation Trust Funds and $8,568 from the A. D. Williams Trust Funds.

"Increased Vulnerability of the Hypertensive Subject to Hemorrhagic Shock."
Dr. R. Wayne Barbee, Associate Professor of Emergency Medicine, was awarded $15,000 from the A. D. Williams Trust Funds.


A. D. Williams Faculty Development Awards

"Gene Expression Profiles in Osteoarthritis Clinical Varients. "
Dr. George F. Moxley, Associate Professor of Internal Medicine, Division of Rheumatology and Immunology, was awarded $2,500 from the A. D. Williams Trust Funds.


APRIL, 2007 AWARDS:

A. D. Williams Research Grants

"Development of a Biphasic Controlled Drug Release Dressing for Chronic Wound Treatment."
Dr. Hu Yang, Assistant Professor of Biomedicalal Engineering, was awarded $15,000 from the A. D. Williams Trust Funds.

"Investigating the Role of TomIl2 in Immune Response and Susceptibility to Infection."
Dr. Sarah H. Elsea, Associate Professor of Pediatrics, was awarded $15,000 from the A. D. Williams Trust Funds.


JANUARY, 2007 AWARDS:

A. D. Williams Multi-School Awards

"Periodontitis, Placental Insufficiency and Infant Outcome."
Dr. Elsie Mainali, Assistant Professor of Pediatrics, was awarded $75,000 as the Principal Investigator of the project. Support comes from the A. D. Williams Trust Funds.

"Streptococcus Sanguinis Vaccine Discovery."
Dr. Ping Xu, Associate Professor in the Philips Institute for Oral and Craniofacial Molecular Biology, was awarded $75,000 as Principal Investigator of the project. Support comes from the A. D. Williams Trust Funds.


A. D. Williams Research Grants

"Extending the Random Forest Methodology for Predicting an Ordinal Response."
Dr. Kellie J. Archer, Assistant Professor of Biostatistics, was awarded $10,342 from the A. D. Williams Trust Funds.

"An Examination of Emergency Department Pediatric Psychiatric Services: A Pilot Study."
Dr. Jennifer F. Brown, Assistant Professor of Integrative Systems, was awarded $11,100: $3,262 from the Bayliss Foundation Trust Funds and $7,838 from the Baruch Foundation Trust Funds.

"Identification of Novel Scaffolds for Lanosterol 14α-Demethylase (CYP51) Inhibitor Design."
Dr. John C. Hackett, Assistant Professor of Medicinal Chemistry, was awarded $14,974 from the A. D. Williams Trust Funds.

"Herpes Virus Membrane Fusion Activity."
Dr. Anthony V. Nicola, Associate Professor of Microbiology and Immunology, was awarded $13,000: $10,000 from the Medical Research Foundation Trust Funds and $3,000 from the A. D. Williams Trust Funds.

"Reliability and Discriminate Validity of Ultrasonography in Measuring Acromiohumeral Distance in Patients with Rotator Cuff Disease."
Dr. Lori A. Michener, Assistant Professor of Physical Therapy, was awarded $14,920 from the A. D. Williams Trust Funds.

"Gallium Arsenide Decreases Thiol Cathepsin Activity."
Dr. Kathleen L. McCoy, Professor of Microbiology and Immunology, was awarded $25,000 from the A. D. Williams Trust Funds.


OCTOBER, 2006 AWARDS:

A. D. Williams Research Grants

"A Pilot Study to Determine the Effect of Selective Serotonin Reuptake Inhibitors on Platelet function and Thrombin Generation Time."
Dr. Cynthia K. Kirkwood, Associate Professor of Pharmacy, was awarded $11,855 from the A. D. Williams Trust Funds.

"Prevent HIV Protease Inhibitor-Induced Atherosclerosis by Berberine."
Dr. Huiping Zhou, Assistant Professor of Microbiology and Immunology, was awarded $15,000: $10,000 from A. D. Williams Trust Funds and $5,000 from the Medical Research Endowment Trust Funds.


JULY, 2006 AWARDS:

A. D. Williams Research Grants

"The Effect of a Five Week Electrical Myostimulation Program in Patients with Heart Failure."
Dr. Ross A. Arena, Assistant Professor of Physical Therapy, was awarded $14,935 from the A. D. Williams Trust Funds.

"Vestibular System and Motor Development in Deaf Children."
Dr. Mary S. Shall, Associate Professor of Physical Therapy, was awarded $5,450 from the A. D. Williams Trust Funds.

"Stress and Anxiety in ADHD: Links to Sensory Modulation Dysfunction."
Dr. Stacey E. Reynolds, Assistant Professor of Occupational Therapy, was awarded $14,700: $11,200 from A. D. Williams Trust Funds and $3,500 from the Feamster Foundation Trust Funds.


A. D. Williams Multi-School Awards

"Aging and Epilepsy: A Multi-disciplinary Approach."
Dr. Severn B. Churn, Associate Professor of Neurology, was awarded $100,000 as Principal Investigator of the project. Support comes from the A. D. Williams Trust Funds.

"Nanofabrication of bone scaffold for cleft palate repair."
Dr. Gary L. Bowlin, Associate Professor of Biomedical Engineering, was awarded $100,000 as Principal Investigator of the project. Support comes from the A. D. Williams Trust Funds.


APRIL, 2006 AWARDS:

"Role of KLF2 in Mouse Erythropoiesis and Globin Expression."
Dr. Joyce A. Lloyd, Associate Professor of Human Genetics, was awarded $15,000: $9,000 from the Harvell Trust funds and $6,000 from the A. D. Williams Trust research funds.

"Altered Receptor Function in Status Epilepticus."
Dr. Severn B. Churn, Associate Professor of Neurology, was awarded $14,992 from the Crump Trust funds.

"The p38 Pathway in Liver Preconditioning."
Dr. Martin J. Mangino, Professor of Surgery, was awarded $14,957 from the A. D. Williams Trust research funds.

"Mechanisms of Ischemia/Reperfusion Injury in Skin."
Dr. Dorne R. Yager, Associate Professor of Surgery, was awarded $14,550 from the A. D. Williams Trust research funds.

"Development of Serotonin-selective Agents as Pharmacological Tools."
Dr. Richard A. Glennon, Professor of Medicinal Chemistry, was awarded $15,000 from the A. D. Williams Trust research funds.


JANUARY, 2006 AWARDS:

Faculty Development Award

"Computerized Analysis of Sensory-based Self-regulation during Maternal Infant Transactions: A Proposal for Technical Support and Training."
Dr. Marie E. Anzalone, Assistant Professor of Occupational Therapy, was awarded $1,175 from A. D. Williams Trust funds.


Research Grants

"Role of Osteoclasts during Tooth Eruption in the c-fos knock out Murine Model."
Dr. Bhavna Shroff, Professor of Orthodontics, was awarded $14,960 from A. D. Williams funds.

"Transcriptional Determinants of Hyperhomocysteinemia in Rat Chromosome 13."
Dr. Ningjun Li, Assistant Professor of Pharmacology and Toxicology, was awarded $15,000 from A. D. Williams Trust funds.


OCTOBER, 2005 AWARDS:

Research Grants

"Social Skills Deficits and Anxiety in Children with Autism Spectrum Disorders."
Dr. Susan K. Williams, Assistant Professor of Psychiatry, was awarded $14,475: $10,975 from the Medical Research Endowment Funds, $2,500 from the Bayliss Foundation, and $1,000 from the A. D. Williams Trust Funds.

"Development of a Resin Modified Bioactive Glass Ionomer Cement for Orthodontic Bonding."
Dr. Eser Tufecki, Assistant Professor of Orthodontics, was awarded $15,000 from the A. D. Williams Trust Funds.

"Transplantation of Adult Neuronal Stem/Progenitor Cells in Rat Brain following Traumatic Brain Injury."
Dr. Dong Sun, Assistant Professor of Neurosurgery, was awarded $15,000 from the A. D. Williams Trust Funds.

"Epidemiology of Antibiotic Use in the University Health System Consortium Network and Bacterial Resistance."
Dr. Amy Pakyz, Assistant Professor of Pharmacy, was awarded $14,700 from the A. D. Williams Trust Funds.

"Children At-risk for Panic Disorders."
Dr. Roxann Roberson-Nay, Assistant Professor of Psychiatry, was awarded $14,974: $8,974 from the Medical Research Endowment Funds and $6,000 from the Friel Foundation.

"Understanding Serious Mental Illness in African-American Families."
Dr. Allen Lewis, Assistant Professor of Rehabilitation Counseling, was awarded $14,155 from the A. D. Williams Trust Funds.

"Characterizing Psychological Distress in Patients Scheduled for Knee Replacement Therapy."
Dr. Daniel T. Riddle, Professor of Physical Therapy, was awarded $14,753: $8,000 from the Blanton Foundation and $6,753 from the A. D. Williams Trust Funds.


JULY, 2005 AWARDS:

"Signaling Differences Accounting for Differential Sensitivity of Tumor Antigen-Sensitized versus Naive T-Lymphocytes to Pharmacologic Activation for Immunotherapy."
Dr. Harry D. Bear, Professor of Surgery, was awarded $15,000 from the A. D. Williams Trust Fund.

"UGTs in Metabolism, Efficacy and Toxicity of Acetaminophen."
Dr. Joseph K. Ritter, Associate Professor of Pharmacology and Toxicology, was awarded $15,000 from the A. D. Williams Trust Fund.

"Cellular Mechanisms of HIV Protease Inhibitor induced macrophage apoptosis."
Dr. Huiping Zhou, Assistant Professor of Microbiology and Immunology, was awarded $14,000 from the A. D. Williams Trust Fund.

"Analysis of the Anti-tumor Potential of Androstene Steroids in Gliomas."
Dr. Martin R. Graf, Assistant Professor of Neurosurgery, was awarded $12,500 from the A. D. Williams Trust Fund.


APRIL, 2005 AWARDS:

Faculty Development Award

"Quantifying Electrodermal Responses in Children."
Dr. Shelly J. Lane, Professor of Occupational Therapy, was awarded $2,500 from the A. D. Williams Trust Funds.


Research Grants

"Neighboring-Nucleotide Effects on Single Nucleotide Polymorphisms in the Mouse Genome."
Dr. Zhongming Zhao, Assistant Professor of Psychiatry, was awarded $14,900 from the A. D. Williams Trust Funds.

"Detection and Quantification of PO2 Transients in Capillaries."
Dr. Alex S. Golub, Associate Professor of Physiology, was awarded $15,000 from the A. D. Williams Trust Funds.

"Cellular Cholesterol Homeostasis in Glomerulosclerosis."
Dr. Siddhartha S. Ghosh, Instructor in Internal Medicine (Division of Nephrology) was awarded $14,981 from the A. D. Williams Trust Funds.

The in vivo Pharmacokinetic Effect of CYP2C9*8."
Dr. Bonny L. Bukaveckas, Assistant Professor of Pharmacy, was awarded $15,000 from the A. D. Williams Trust Funds.


JANUARY, 2005 AWARDS:

Multi-School Award

"The VCU Mouse Microarray Immunological Signal Transduction Initiative."
Dr. Paul M. Fawcett, Assistant Professor of Internal Medicine, (Division of Infectious Diseases) as the Principal investigator, was awarded $100,000.


Research Grants

"Structural and Functional Analysis of NgR Mediated Signaling."
Dr. William A. Barton, Research Assistant Professor of Medicinal Chemistry, was awarded $15,000 by the Crump Foundation trust funds.

"Role of GFI-1B in Erythroid Cells."
Dr. Stephen T. Sawyer, Professor of Pharmacology and Toxicology, was awarded $15,000, provided in part by the Harvell Foundation trust funds and in part by the Friel Foundation trust funds.

"Effects of Preeclampsia and Gestational Diabetes on the Placental ATP Binding Cassette Efflux Transporters MRP2, ABCG2, and MDR1."
Dr Phillip M. Gerk, Assistant Professor of Pharmaceutics, was awarded $15,000 by the Medical Research Endowment trust funds.

"The Effectiveness of the Beckman Oral-Motor Intervention for Children with Feeding Impairments."
Dr. Dianne Koontz Lowman, Associate Professor of Occupational Therapy, was awarded $13,906 by the A. D. Williams trust funds.

"The Role of CD44 Isoforms in Immunotherapy of Melanoma."
Dr. Robert J. McKallip, Assistant Professor of Microbiology and Immunology, was awarded $15,000 by the A. D. Williams trust funds.

"Basis of Individual Variability in Responses to Nicotine."
Dr. Susan E. Robinson, Professor of Pharmacology and Toxicology, was awarded $15,000 by the A. D. Williams trust funds.

"Candidate Genes for Anxiety Disorders."
Dr. John M Hettema, Assistant Professor of Psychiatry, was awarded $15,000, provided in part by the Baruch Foundation trust funds and in part by the A. D. Williams trust funds.

"Pilot Study to Determine the Effect of Antiplatelet Therapy with Clopidogrel on Vascular Inflammation in Patients with Diabetes Mellitus."
Dr. James A. Arrowood, Professor of Internal Medicine (Division of Cardiology), was awarded $15,000, provided in part by the Medical Research Endowment trust funds and in part by the A. D. Williams trust funds.

"Chemokine Receptor CCR5 Antagonists as Novel Anti-HIV-1 Agents."
Dr. Yan Zhang, Assistant Professor of Medicinal Chemistry, was awarded $15,000 by the A. D. Williams trust funds.

"Cross-sensitization between the Urinary Bladder and Colon after Inflammation."
Dr. Liya Qiao, Assistant Professor of Physiology, was awarded $15,000 by the A. D. Williams trust funds.

"Understanding the Regulation of FAS and FASL post 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) Exposure."
Dr. Narenda P. Singh, Assistant Professor of Pharmacology and Toxicology, was awarded $15,000 by the A. D. Williams trust funds.



JULY, 2004 AWARDS:

"Oral Health Care in the Medical Setting."
Dr. Tegwyn L. Hughes, Assistant Professor of Pediatric Dentistry, was awarded $15,000; $2,500 from the Feamster Trust Funds, $2,500 from the Bayliss Trust Funds, and $10,000 from the A. D. Williams Trust Funds.

"Structural Proteomics and Intracellular Localization of the Human TRM5 Protein."
Dr. W. Michael Holmes, Professor of Microbiology and Immunology, was awarded $14,885 from the A. D. Williams Trust Funds.

"Role of Cholesterol Transporter in Macrophages."
Dr. Shulin Ren, Assistant Professor of Internal Medicine (Division of Gastroenterology), was awarded $15,000 from the A. D. Williams Trust Funds.

"Behavioral and Genetic Markers of Drug Addiction in an Adolescent Murine Model."
Dr. Edwin van den Oord, Associate Professor of Psychiatry, was awarded $14,991 from the A. D. Williams Trust Funds.



APRIL, 2004 AWARDS:

Faculty Development Award:

?Methods Used to Evaluate Olfactory Function.?
Dr. Richard M. Costanzo, Professor of Physiology, was awarded $2,500.


Research Grant Awards:

?Psychological Impact of Orofacial Injury.?
Daniel M. Laskin, Professor of Oral & Maxillofacial Surgery, was awarded $15,000 from the A. D. Williams Trust Fund.

?Identification of Vaccine Candidates in Streptococcus sanguis.?
Dr. Todd Kitten, Assistant Professor in the Philips Institute, School of Dentistry, was awarded $15,000 from the Research Endowment Trust Funds and the A. D. Williams Trust Fund.

?Oral Contraceptives in the Metabolic Syndrome.?
Dr. Kai J. Cheang, Assistant Professor of Pharmacy, was awarded $15,000 from the A. D. Williams Trust Fund.

?CAST (Cesarean after Sphincter Tear) Pilot Study.?
Dr. Catherine Nichols, Assistant Professor of Obstetrics and Gynecology, was awarded $15,000 from the Friel Foundation Trust Fund and the A. D. Williams Trust Fund.


JANUARY, 2004 AWARDS:

"Effect of Therapeutic Ultrasound on Cytokine Induction in Human Monocytes."
Dr. Sheryl Finucane, Assistant Professor of Physical Therapy, School of Allied Health Professions, was awarded $13,410 from the A. D. Williams Trust Funds.

"Effect of Chronic Ethanol Consumption on Endogenous Adult Neural Stem Cells."
Dr. Ann Rice, Instructor in Neurosurgery, School of Medicine, was awarded $11,100 from the Medical Research Endowment Trust Funds.

"Effect of perinatal opioid addiction treatment on brain myelination."
Dr. Carmen Sato-Bigbee, Associate Professor of Biochemistry, School of Medicine, was awarded $15,000; $10,000 from the Baruch Foundation Trust Funds and $5,000 from the A. D. Williams Trust Funds.

"Electrospun Collagen Type II Scaffold for Engineering a Cartilaginous Construct in the Shape of a Human Ear: A Feasibility Study."
Dr. Cary Canoun, Assistant Professor of Surgery, School of Medicine, was awarded $13,725 from the A. D. Williams Trust Funds.

"Effect of L-Arginine Infusion on the Inflammatory Response Following Hemorrhagic Shock and Abdominal Compartment Syndrome in Swine."
Dr. Ajai K. Malhotra, Assistant Professor of Surgery, School of Medicine, was awarded $15,000 from the A. D. Williams Trust Funds.



OCTOBER, 2003 AWARDS:

"Role of Hypoxia Inducible Factor-1 in Microvascular Ischemia/Reperfusion."
Dr. Ramesh Natarajan, Assistant Professor of Internal Medicine (Division of Pulmonary and Critical Care Medicine) was awarded $15,000 from the A. D. Williams Trust funds.

"Design of Aldehydic Compounds as Anti-sickling Agents."
Dr. Martin K. Safo, Assistant Professor of Medicinal Chemistry, was awarded $9,700 from the Harvell Foundation Trust funds.


JULY, 2003 AWARDS:

Multi-School Award:

"Serpin Complexes: Formation, Properties, and Links to Angiogenesis and Alzheimer?s Disease."
Dr. H. T. Wright, Professor of Biochemistry is the Principle Investigator of a multi-school award for $138,707 provided by the A. D. Williams Trust Funds.

Research Grants:

"E3B1 and CDK6 in Adhesion and Migration."
Dr. W. Andrew Yeudall of the Philips Institute of Oral and Craniofacial Molecular Biology, School of Dentistry was awarded $15,000 from the A. D. Williams Trust Funds.

"The Effects of a Therapeutic Martial Arts Program on Youth in Residential Psychiatric Treatment."
Dr. Brian Hill, Assistant Professor of Psychiatry, was awarded $11,797 from the A. D. Williams Trust Funds.

"Prospective Randomized Placebo Controlled Study of Empiric Treatment of Delirium with Donepezil in Mechanically Ventilated ICU Patients."
Dr. Marjolein de Wit, Assistant Professor of Internal Medicine (Division of Pulmonary Medicine and Critical Care) was awarded $15,000 from the A. D. Williams Trust Funds.

"Intravenous Drug Self-Administration in Rats Perinatally Exposed to Opioids."
Dr. Katherine Nicholson, Assistant Professor of Pharmacology and Toxicology, was awarded $13,460 from the A. D. Williams Trust Funds.

"Non-Invasive Acoustic Measurement of Intracranial Pressure."
Dr. Martin Lenhardt, Professor of Biomedical Engineering, was awarded $14,000; $3,000 from the Friel Foundation Trust Funds and $11,000 from the A. D. Williams Trust Funds.

"Crystallographic Analysis of KsgA/RNA Complexes."
Dr. Jason P. Rife, Assistant Professor of Medicinal Chemistry, was awarded $15,000 from the A. D. Williams Trust Funds.


APRIL, 2003 AWARDS:

"Short-Term Reliability of Oxygen Uptake On-Kinetics."
Dr. Ross Arena, Assistant Professor of Physical Therapy, was awarded $6,830 from A. D. Williams Trust funds.

"Characterization of Fur and Reg regulons of Porphyromonas gingivalis W83."
Dr. Janina P. Lewis, Assistant Professor of Molecular and Oral Biology, was awarded $15,000: $2,000 from the Friel Trust Fund and $13,000 from the A. D. Williams Trust fund.

"Assessing the Psychometric Properties of the Maternal Infant Responsiveness Instrument (MRI)."
Dr. Linda Amankwaa, Assistant Professor of Maternal Child Care Nursing, was awarded $14,801: $10,000 from Bayless Foundation Trust Funds and $4,801 from the A. D. Williams Trust Funds.

"The Effects of Fine Particulate Air Pollution Components on Human Mast Cell Mediator Release."
Dr. Christopher L. Kepley, Assistant Professor of Internal Medicine (Division of Rheumatology and Immunology), was awarded $15,000 from the A. D. Williams Trust Funds.

"Engineering Bladder Tissue Using Electrospun Collagen Nanofibers."
Dr. Harry P. Koo, Associate Professor of Surgery, was awarded $14,812 from the A. D. Williams Trust Funds.

"Molecular Mechanisms of the Anti-carcinogenic Effects of Estradiol and Its Major Metabolites in Human Endometrial Carcinoma Cells."
Dr. Ning Gao, Assistant Professor of Pharmaceutics, was awarded $15,000 from the A. D. Williams Trust Funds.

"Kinetics and Mechanisms of Lung Disposition for Inhaled Insulin in Rats."
Dr. Masahiro Sakagami, Assistant Professor of Pharmaceutics, was awarded $15,000: $9,750 from the Baruch Founndation Trust funds and $5,250 from the A. D. Williams Trust Funds.

"New Molecular and Cellular Properties of Serpin Complexes."
Dr. H. T. Wright, Professor of Biochemistry, was awarded $15,000: $9,000 from the Blanton Foundation Trust funds and $6,000 from the A. D. Williams Trust funds.

"Racial and Ethnic Differences in the Etiology of Type 2 Diabetes in the United States." Dr. John N. Clore, Professor of Internal Medicine (Division of Endocrinology and Metabolism), was awarded $15,000 from the A. D. Williams Trust Funds.


JANUARY, 2003 AWARDS:

"Gene Expression in Developmental Cortical Malformations Associated with Epilepsy."
Dr. Kimberley M. Jacobs, Assistant Professor of Anatomy and Neurobiology, was awarded $14,819 from the A. D. Williams Trust Funds.

"Genetic Basis of Osteoarthritis."
Dr. George Moxley, Associate Professor of Internal Medicine (Division of Rheumatology, Allergy, and Immunology), was awarded $15,000 from the Medical Research Endowment Trust Funds.

Relationships among Depressive Symptoms, Quality of Life, Neuroendocrine Mediators, and HIV symptoms."
Dr. Christopher L. Coleman, Assistant Professor of Integrated Systems, was awarded $15,000 from the A. D. Williams Trust Funds.


OCTOBER, 2002 AWARDS:

"The Effects of Melatonin on Sleep in HIV: A Feasibility Pilot Project."
Dr. Donna H. Taliaferro, Associate Professor of Adult Health Nursing, was awarded $15,000 from the Medical Research Endowment Funds.

"Hip Motor-Control Assessment: Comparing Physical Exam Techniques with Quantitative Motion Analysis in Normal Subjects and Subjects with Lower Limb Musculoskeletal Injury."
Dr. Peter E. Pidcoe, Assistant Professor of Physical Therapy, was awarded $14,990 from the A. D. Williams Trust Funds.

"TGF? Is an Endogenous Radio Protective Factor in Esophageal Cancer Cells."
Dr. Theodore D. Chung, Associate Professor of Radiation Oncology, was awarded $15,000 from the A. D. Williams Trust Funds.

"Nitric Oxide Regulation of Endothelial Interleukin-8 Expression."
Dr. Alpha A. Fowler, Professor of Internal Medicine (Division of Pulmonary and Critical Care), was awarded $15,000 from the A. D. Williams Trust Funds.


JULY, 2002 AWARDS:

Faculty Development Award

"Probing the Outer Vestibule Structure of the HERG Channel Using a Recombinant Peptide Toxin, BeKm-1."
Dr. Gea-Ny Tseng, Associate Professor of Physiology, was awarded $2,500 from the A. D. Williams Trust Funds.

Research Grant Awards

"Correlation of Proliferation of Adult Neural Stem/Progenitor Cells and Recovery from Cognitive Deficits Following Traumatic Brain Injury."
Dr. Ann C. Rice, Instructor of Surgery, was awarded $14,695. $10,000 was from the Crump Trust Funds and $4,695 from the A. D. Williams Trust Funds.

"Effect of Emphysema on Oxygen Transport in Skeletal Muscle."
Dr. Roland N. Pittman, Professor of Physiology, was awarded $15,000 from A. D. Williams Trust Funds.

"Dendritic Cell-Based HIV Vaccine."
Dr. Elsie S. Mainali, Assistant Professor of Pediatrics, was awarded $10,000 from the Feamster Foundation Trust Funds and $5,000 from the A. D. Williams Trust Funds.

"Duration of Action of a Peri-tubation, Single Oral Application of Chlorhexidine on Oral Microbial Flora."
Dr. Mary Jo Grap, Associate Professor of Adult Health Nursing, was awarded $14,888 from the A. D. Williams Trust Funds.

"Candidate Gene Studies of Anorexia Nervosa."
Dr. Brien Riley, Assistant Professor of Psychiatry, was awarded $14,920 from A. D. Williams Trust Funds.

"Trigger Films as an Aide to Developing, Enabling and Assessing Anesthesia Clinical Instructors."
Dr. C. J. "Chuck" Biddle, Professor of Nurse Anesthesia, was awarded of $10,551 from the A. D. Williams Trust Funds.


APRIL, 2002 AWARDS:

"Anal Sphincter Injury in Women With Urinary Incontinence and Pelvic Organ Prolapse."
Dr. Catherine Nichols, Assistant Professor of Obstetrics & Gynecology, was awarded $5,000 from Friel Foundation Funds and $10,000 from the A. D. Williams Trust Funds.

"Deaf Gay Men Managing HIV/AIDS."
Dr. R. Kevin Mallinson, Assistant Professor of Adult Health Nursing, was awarded $10,000 from Medical Research Endowment Trust Funds and $4,431 from A. D. Williams Trust Funds.

"A Randomized, Placebo-Controlled Trial of the Efficacy of Zinc Therapy in Cancer Patients with Chemotherapy-Related Taste & Smell Disorders."
Dr. Laurel Lyckholm, Assistant Professor of Internal Medicine (Division of Hematology & Oncology) was awarded $12,168 from A. D. Williams Trust Funds.

"Curriculum Content in Authorship and Publication Practices."
Dr. Francis L. Macrina, Professor of Dentistry, was awarded $11,100 from A. D. Williams Trust Funds.


JANUARY, 2002 AWARDS:

Faculty Development Awards

"A Canine Model of Chronic Heart Failure by Multiple Sequential Coronary Microembolization."
Dr. Robert S. D. Higgins, Associate Professor of Surgery, was awarded $2,500 from the A. D. Williams Trust Funds.

"Respiratory Gated Radiotherapy Using Intrapulmonary Radio-opaque Markers."
Dr. Vijay R. Kini, Assistant Professor of Radiation Oncology, was awarded $2,500 from the A. D. Williams Trust Funds.

A. D. Williams Research Grants

"Health Care Use by Infants During the First Months of Life."
Dr. Gail Cohen, Assistant Professor of Pediatrics, was awarded $14,749 from the Franklin Foundation Trust.

"Inner Strength in Women with Transplantation." Dr. Gayle Roux , Assistant Professor of Maternal Child Health Nursing, was awarded $15,000 from the A. D. Williams Trust Funds.

"Mitochondrial DNA Mutations and Deafness."
Dr. Glenn C. Van Tuyle, Associate Professor of Biochemistry and Molecular Biophysics, was awarded $5,000 from the Baruch Foundation Trust Funds and $10,000 from the Medical Research Endowment Trust Funds.

"Molecular Identification of Sodium/Hydrogen Exchangers in Rat Taste Receptor Cells: Implications for Sour Taste."
Dr. Anna K. Vinnikova, Assistant Professor of Internal Medicine (Division of Nephrology), was awarded $15,000 from the A. D. Williams Trust Funds.

Multi-School Award

"Tetrahydroisoquinolines as Novel Psychotherapeutic Agents"
Dr. Richard A. Glennon. Professor of Medicinal Chemistry, as Principal Investigator, was awarded $138,641 from the A. D. Williams Trust Funds.

This is the initial award being made under this new category of A. D. Williams research support.


SEPTEMBER, 2001 AWARDS:

Research Grant Awards:

"Effects of Resistance Exercise on Cancer-Induced Muscle Wasting in Rats."
Dr. Sadeeka Al-Majid, Assistant Professor of Adult Health Nursing, was awarded $15,000 from the A. D. Williams Trust Funds.

"Pathogenesis of Pressure Ulcers."
Dr. Robert F. Diegelmann, Professor of Biochemsitry and Molecular Biophysics, was awarded $9,985 from the A. D. Williams Trust Funds.

"Medical Error in Primary Care: Cause and Prevention."
Dr. Anthony J. Kuzel, Professor of Family Medicine, was awarded $6,927 from the A. D. Williams Trust Funds.

"A Microscopic Study of Bone Sialoprotein on Biomaterials for Bone Tissue Engineering."
Dr. Peter C. Moon, Associate Professor of General Practice, was awarded $15,000 from the A. D. Williams Trust Funds.

"Assessment of the Behavioral Effects of TDIQ, a Potential Pharmacotherapy for Cocaine Abuse."
Dr. Richard Young, Associate Professor of Medicinal Chemistry, was awarded $15,000 from the both the Butler Foundation Funds and the A. D. Williams Trust Funds.